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    hADORA2B/CHO GPCR細胞

    hADORA2B/CHO GPCR細胞

    型    號: CBP71368
    報    價:
    分享到:

    hADORA2B/CHO

    CBP71368hADORA2B/CHO GPCR細胞的詳細資料:

    RQP71368
    I. Background

    The adenosine receptors ADORA2B is Gs and Gq/G11-coupled GPCR expressed in the large intestine, cecum, and urinary bladder. ADORA2B receptor mediates relaxation to adenosine in human small coronary arteries which is independent of NO but dependents in part on a K+-sensitive mechanism. Pharmacological or molecular biologic activation of ADORA2B receptor may prevent glomerular remodeling associated with glomerulosclerosis, renal disease, and abnormal growth associated with hypertension and diabetes.


    II. Introduction
    Host Cell:

    CHO

    Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
    Freeze Medium:90% FBS+10% DMSO
    Culture Medium:N/A
    Mycoplasma Status:Negative
    Storage:Liquid nitrogen immediately upon delivery
    Application(s):

    Functional assay for hADORA2B receptor

    Transducer:  Gs

    Ⅲ. Description of Host Cell Line
    Organism:Hamster
    Tissue:Ovary
    Morphology: Epithelial
    Growth Properties: Adherent

    Ⅳ. Representative Data

    CBP71368.png

    Figure 1. NECA efffect on hA2B clone 11.



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