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    CB2/CHO GPCR細胞

    CB2/CHO GPCR細胞

    型    號: CBP71366
    報    價:
    分享到:

    CB2/CHO

    CBP71366CB2/CHO GPCR細胞的詳細資料:

    CBP71366
    I. Background
    The Cannabinoid receptor 2 (CNR2) is a Gi/o-coupled GPCR expressed in spleen, tonsils, bone marrow and peripheral blood leukocytes.  There is one report that cannabinoid-induced inhibition of helper T cell activation is lost in macrophages obtained from CNR2 knockout mice.  CNR2 is a potential therapeutic target in the treatment of various disease conditions, such as pain, multiple sclerosis, vascular disease, Parkinson's disease, and other central nerve system disorders.

    II. Introduction
    Host Cell:

    CHO

    Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
    Freeze Medium:90% FBS+10% DMSO
    Culture Medium:N/A
    Mycoplasma Status:Negative
    Storage:Liquid nitrogen immediately upon delivery
    Application(s):

    Functional assay for CB2 receptor

    Transducer:Gi

    Ⅲ. Description of Host Cell Line
    Organism:Hamster
    Tissue:Ovary
    Morphology: Epithelial
    Growth Properties: Adherent

    Ⅳ. Representative Data

    CBP71366 數據圖.png

    Figure 1. CP55940 efffect on CHO-CB2 clone 24.



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