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    CCR8/CHO GPCR細胞

    CCR8/CHO GPCR細胞

    型    號: CBP71364
    報    價:
    分享到:

    CCR8/CHO

    CBP71364CCR8/CHO GPCR細胞的詳細資料:

    CBP71364
    I. Background

    C-C chemokine receptor type 1 (CCR8) is a G protein-coupled receptor member of the CC chemokine subfamily of

    receptors. Following interaction with its specific chemokine ligands, like macrophage inflammatory protein 1 alpha

    (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), and monocyte

    chemoattractant protein 3 (MCP-3), it triggers the onset of a process known as chemotaxis. GenScript’s human

    CCR8-expressing stable subline is guaranteed to function properly in the calcium flux assay.



    II. Introduction
    Host Cell:

    CHO

    Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
    Freeze Medium:90% FBS+10% DMSO
    Culture Medium:F12K+10%FBS+5ug puromycin
    Mycoplasma Status:Negative
    Storage:Liquid nitrogen immediately upon delivery
    Application(s):

    Functional assay for CCR8 receptor

    Transducer:Gi

    Ⅲ. Description of Host Cell Line
    Organism:Hamster
    Tissue:Ovary
    Morphology: Epithelial
    Growth Properties: Adherent

    Ⅳ. Representative Data

     COBIOER

    Figure 1. Recombinant CCR8/CHO constitutively expressing CCR8.

     COBIOER

    Figure 2. CCL1 effect on CCR8/CHO clone 36.




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