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    CXCR1/CHO GPCR細胞

    CXCR1/CHO GPCR細胞

    型    號: CBP71360
    報    價:
    分享到:

    CXCR1/CHO

    CBP71360CXCR1/CHO GPCR細胞的詳細資料:

    CBP71360
    I. Background
    CXCR1 (C-X-C Motif Chemokine Receptor 1) is a Protein Coding gene.The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

    II. Introduction
    Host Cell:

    CHO

    Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
    Freeze Medium:90% FBS+10% DMSO
    Culture Medium:F12K+10%FBS+5ug/ml puromycin
    Mycoplasma Status:Negative
    Storage:Liquid nitrogen immediately upon delivery
    Application(s):

    Functional assay for CXR1 receptor

    Transducer:Gi/Gq

    Ⅲ. Description of Host Cell Line
    Organism:Hamster
    Tissue:Ovary
    Morphology: Epithelial
    Growth Properties: Adherent

    Ⅳ. Representative Data

    CBP71360.png

    Figure 1. IL-8 efffect on CHO-CXCR1 clone 6.






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